来源:新葡萄娱乐官网版网站 发布时间:2017-09-29 浏览次数:8348

简介


胡莲美,女,山东省邹城市人,医学博士,副教授,硕士研究生导师。

目前主要从事动物代谢病及中毒病相关的研究工作。担任Sci Total Environ,Life Science, Biol Trace Elem Res等杂志审稿人。 发表论文60余篇, 申请专利2项, 参编专著3部, 获“广东省科技进步二等奖”1项,“广州市科技进步一等奖”1项。



学历及培训经历


2002 年 08 月-2005 年 06 月 第一军医大学(现南方医科大学)基础医学系 博士研究生  朴英杰教授

1999 年 07 月-2002 年 06 月 华南农业大学 新葡萄娱乐官网版网站 硕士研究生  唐兆新教授

1994 年 09 月-1998 年 06 月 莱阳农学院(现青岛农业大学)兽医系 本科生


工作经历


2017/03 -至今   新葡萄娱乐官网版网站临床兽医系    副教授

2016/03 -2017/03美国佐治亚大学新葡萄娱乐官网版网站            访问学者

2016/ 01-2016/ 03   新葡萄娱乐官网版网站临床兽医系    副教授

2010/03 - 2015/12 新葡萄娱乐官网版网站临床兽医系    讲师

2005/07 - 2009/09    解放军第458医院全军肝病中心      主治医师


研究领域


动物营养代谢病及中毒病;天然海洋药物开发。


承担科研项目情况


1.国家自然科学基金委员会, 国际(地区)合作与交流项目, 32161160304, 蕨藻硫酸多糖靶向COX-2介导的铁死亡重塑免疫代谢的分子机制研究, 2022/01/01 – 2024/12/31, 140万元, 在研, 主要参加;

2.广东省资源厅项目, 202153,海藻多糖免疫增效抗肿瘤新型营养剂的研发,2021/05-2023/05,200万元,在研,主要参加;

3.广东省资源厅项目, 2020038,海藻多糖调控肿瘤代谢的特征全谱模型的构建及应用,2020/01-2022/01,200万元,已结题,主要参加;

4.广州市民生科技计划项目,20180302003,靶向肠道菌群海藻活性多糖的精深高值化关键技术研究,2018/04-2021/03,100万元,已结题,主要参加;

5.国家自然科学基金面上项目,31572585,线粒体自噬在高铜诱导肉鸡病的机理研究, 2016/01-2019/12, 65万元, 已结题, 参加;

6.国家自然科学基金面上项目,31502131,TRPC在肉鸡腹水综合征中的应用,2016/01-2018/12,21万元,已结题,参加;

7.国家自然科学基金青年基金,31402264, Msr介导肉鸡砷毒性氧化应激与蛋白修复机制研究,2015/01-2017/12, 25万元, 已结题, 主持;

8.广东省科技计划项目, 2011B020306009, 重组硫氧还蛋白治疗肉鸡内毒素血症的效果评价,2012/01-2013/12, 8万元, 已结题, 主持。


代表论著(*通讯作者)


1.Gaolong Zhong#,Gan Rao, Lixuan Tang, Shaofeng Wu, Zhaoxin Tang, Riming Huang , Ziyan Ruan, Lianmei Hu*. Combined effect of arsenic and polystyrene-nanoplastics at environmentally relevant concentrations in mice liver: Activation of apoptosis, pyroptosis and excessive autophagy. Chemosphere 2022,300:134566.( IF 2021=8.943)

2.Gaolong Zhong#, Fang Wan, Juan Lan, Xuanxuan Jiang, Shaofeng Wu, Jiaqiang Pan, Zhaoxin Tang, Lianmei Hu*. Arsenic exposure induces intestinal barrier damage and consequent activation of gut-liver axis leading to inflammation and pyroptosis of liver in ducks. Sci Total Environ 2021, 788:147780. (IF 2021=10.753)  

3.Gaolong Zhong #, Fang Wan #, Shaofeng Wu, Xuanxuan Jiang, Zhaoxin Tang, Xiaoyong Zhang, Riming Huang*, Lianmei Hu*. Arsenic or/and antimony induced mitophagy and apoptosis associated with metabolic abnormalities and oxidative stress in the liver of mice. Sci Total Environ 2021, 777:146082. (IF 2021=10.753)    

4.Shaofeng Wu#, Wenlan Yu#, Xuanxuan Jiang, Riming Huang, Xiaoyong Zhang, Juan Lan, Gaolong Zhong, Fang Wan, Zhaoxin Tang, Lianmei Hu*. Protective effects of curcumin on ATO-induced nephrotoxicity in ducks in relation to suppressed autophagy, apoptosis and dyslipidemia by regulating oxidative stress. Ecotoxicol Environ Saf. 2021, 219: 112350. (IF 2021=7.129)

5.Fang Wan#, Gaolong Zhong, Shaofeng Wu, Xuanxuan Jiang, Jianzhao Liao, Xiaoyong Zhang, Hui Zhang, Khalid Mehmood, Zhaoxin Tang, Lianmei Hu*. Arsenic and antimony co-induced nephrotoxicity via autophagy and pyroptosis through ROS-mediated pathway in vivo and in vitro. Ecotoxicol Environ Saf. 2021, 221: 112442  (IF 2021=7.129)

6.Shaofeng Wu#, Gaolong Zhong, Fang Wan, Xuanxuan Jiang, Zhaoxin Tang, Ting Hu, Gan Rao, Juan Lan, Riaz Hussain, Lixuan Tang, Hui Zhang, Riming Huang, Lianmei Hu*. Evaluation of toxic effects induced by arsenic trioxide or/and antimony on autophagy and apoptosis in testis of adult mice. Environ Sci Pollut Res Int. 2021, May 20. doi: 10.1007/s11356-021-14486-1. (IF 2021= 5.19) 

7.Xuanxuan Jiang#, Wenlan Yu#, Shaofeng Wu, Lixuan Tang, Gaolong Zhong, Fang Wan, Juan Lan, Hui Zhang, Jiaqiang Pan, Zhaoxin Tang, Xiaoyong Zhang, Lianmei Hu*, Riming Huang*. Arsenic (III) and/or Antimony (III) induced disruption of calcium homeostasis and endoplasmic reticulum stress resulting in apoptosis in mice heart. Ecotoxicol Environ Saf 2021; 220: 112394.   (IF 2021=7.129)

8.Gaolong Zhong #, Fang Wan, Zhijun Ning, Shaofeng Wu, Xuanxuan Jiang, Zhaoxin Tang, Riming Huang*, Lianmei Hu*. The protective role of autophagy against arsenic trioxide-induced cytotoxicity and ROS-dependent pyroptosis in NCTC-1469 cells. J Inorg Biochem 2021, 217: 111396. (IF 2021=4.336)

9.Gaolong Zhong #, Ying He#, Fang Wan, Shaofeng Wu, Xuanxuan Jiang, Zhaoxin Tang, Lianmei Hu*. Effects of Long-Term Exposure to Copper on the Keap1/Nrf2 Signaling Pathway and Msr-Related Redox Status in the Kidneys of Rats. Biol Trace Elem Res 2021, Jan 22. (IF 2021= 4.081)

10.Fang Wan#, Gaolong Zhong, Zhijun Ning, Jianzhao Liao, Wenlan Yu, Congcong Wang, Qingyue Han, Ying Li, Jiaqiang Pan, Zhaoxin Tang, Riming Huang*, Lianmei Hu*. Long-term exposure to copper induces autophagy and apoptosis through oxidative stress in rat kidneys. Ecotoxicol Environ Saf 2020, 190: 110158. (IF 2021=7.129)

11.Gaolong Zhong#, Fang Wan, Hao Yan, Zhijun Ning, Congcong Wang, Ying Li, Jiaqiang Pan, Zhaoxin Tang, Zengming Yang, Riming Huang, Lianmei Hu*. Methionine Sulfoxide Reductases Are Related to Arsenic Trioxide-Induced Oxidative Stress in Mouse Liver. Biol Trace Elem Res 2020, 195(2): 535-543. (IF 2021= 4.081)

12.Congcong Wang#, Zhijun Ning, Fang Wan, Riming Huang, Limin Chao, Zhenlong Kang, Fan Yang, Gaolong Zhong, Ying Li, Jiaqiang Pa, Zhaoxin Tang, Lianmei Hu*. Characterization of the cellular effects and mechanism of arsenic trioxide-induced hepatotoxicity in broiler chickens. Toxicol In Vitro 2019, 61: 104629. (IF 2021= 3.685)

13.Yu Han#, Yulin Wu, Guoqiang Li, Meiying Li, Ru Yan, Zhenlin Xu, Hongtao Lei, Yuanming Sun, Xuewe Duan, Lianmei Hu*, Riming Huang*, Structural characterization and transcript-metabolite correlation network of immunostimulatory effects of sulfated polysaccharides from green alga Ulva pertusa. Food Chemistry, 2020.128537. (IF 2020= 7.514)

14.Meixia Guo#, Xiaoyong Zhang, Meiying Li, Taotao Li, Xuewu Duan, Dandan Zhang, Lianmei Hu*, Riming Huang*. Label-free proteomic analysis of molecular effects of 2-methoxy-1,4-naphthoquinone on penicillium italicum. International Journal of Molecular Sciences, 2019,20(14),3459. (IF 2020= 5.923)

15.Huili Hao#, Yu Han, Lihong Yang, Lianmei Hu, Xuewu Duan, Xian Yang, Riming Huang*. Structural characterization and immunostimulatory activity of a novel polysaccharide from green alga Caulerpa racemosa var peltata. Int J Biol Macromol 2019; 134: 891-900. (IF 2020= 6.953)